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Summer 2021Healthcare

Matrubials

Developing milk-inspired therapeutics for infectious diseases

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About Matrubials

Matrubials is an anti-infectives company, focused on human milk peptides as therapeutics to address antimicrobial resistance and modern diseases. Currently the global rise in severe bacterial infections and the drying pipeline of effective treatments are burdensome for healthcare and economics. Sculpted by evolution, milk, first food for the newborn, provides an exemplary solution to address the nutritive and protective challenges an infant is faced with. The anti-pathogenic molecules from milk can be developed into therapeutics geared towards all-age diseases. Our first indication is bacterial vaginosis, a bacterial dysbiosis related inflammation that results in recurrent infections, disruption of homeostasis and long-term clinical complications in women of reproductive age, including but not limited to preterm births, fertility issues and increased rates of STDs. Our next inflection point is the evaluation of rapidly acting and selective candidate peptides in pre-clinical host impact and early safety studies, which can aid clinical and portfolio development towards topical applications.

Quick facts

YC Batch
Summer 2021
Founded
2018
Headquarters
Davis, CA
Team size
4
Industry
Healthcare • Healthcare -> Drug Discovery and Delivery
Tags
ai-powered-drug-discovery, women's-health, therapeutics
Website
matrubials.com
Profiles
LinkedIn

Founders

Ishita Shah
Founder
Ishita M. Shah, PhD, is the CEO and co-founder of Matrubials, a spin-out from UC Davis, Foods for Health Institute. As the Associate Director (Microbial Programs) at FFHI, she has investigated the role of milk components…
Bruce German
Founder
Bruce is a PhD from Cornell University, Distinguished Professor at the University of California, Davis and director of the Foods for Health Institute. His research focuses on the evolution of lactation and the biological…
Carlito Lebrilla
Founder
Dr. Carlito B. Lebrilla is a Distinguished Professor at the University of California, Davis in the Department of Chemistry and Biochemistry and Molecular Medicine in the School of Medicine. His research is in Analytical…
David Mills
Founder
David A. Mills is a Professor in the Department of Food Science & Technology at the UC Davis. Dr. Mills studies the molecular biology and ecology of bacteria that play an active role in gut health or fermented foods. He …

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